Panama City pairs a glittering skyline with Casco Viejo, a UNESCO-listed colonial quarter of plazas and restored mansions. Most visitors come for the Panama Canal, and there are good-value hotels across the modern districts.
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Panama City is the gateway to the Panama Canal — the Miraflores Locks visitor center is a short drive from downtown, and canal cruises embark or call on both the Pacific and Caribbean sides.
The historic old town of plazas, rooftop bars and boutique hotels in restored buildings.
Central neighborhoods with many good-value hotels, restaurants and the metro nearby.
The bay-front boulevard and Cinta Costera, with high-rise hotels and sea views.
Upscale towers, big hotels and shopping on the waterfront.
A causeway at the Pacific entrance to the canal, with the Biomuseo and views of passing ships.
Zoom and pan the map to compare hotel prices by neighborhood; rates come live from the booking sites.
The dry season, roughly mid-December to April, is the most popular time and brings the highest rates; the rainy season is cheaper, with showers most afternoons.
El Cangrejo and Bella Vista have many good-value hotels close to restaurants and the metro.
The Miraflores Locks visitor center, a short drive from downtown, has viewing decks where you can watch ships pass through.
Check whether your ship leaves from the Pacific or Caribbean side; Panama City hotels suit Pacific departures, and cruise lines often run transfers to Colón on the Caribbean side.